Genetics
Genetics

3 Questions: Building predictive models to characterize tumor progression

Assistant Professor Matthew Jones is working to decode molecular processes on the genetic, epigenetic, and microenvironment levels to anticipate how and when tumors evolve to resist treatment.

AI to help researchers see the bigger picture in cell biology

By providing holistic information on a cell, an AI-driven method could help scientists better understand disease mechanisms and plan experiments.

3 Questions: Using computation to study the world’s best single-celled chemists

Assistant Professor Yunha Hwang utilizes microbial genomes to examine the language of biology. Her appointment reflects MIT’s commitment to exploring the intersection of genetics research and AI.

How to more efficiently study complex treatment interactions

A new approach for testing multiple treatment combinations at once could help scientists develop drugs for cancer or genetic disorders.

An ancient RNA-guided system could simplify delivery of gene editing therapies

The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.

With generative AI, MIT chemists quickly calculate 3D genomic structures

A new approach, which takes minutes rather than days, predicts how a specific DNA sequence will arrange itself in the cell nucleus.

A causal theory for studying the cause-and-effect relationships of genes

By sidestepping the need for costly interventions, a new method could potentially reveal gene regulatory programs, paving the way for targeted treatments.

A more effective experimental design for engineering a cell into a new state

By focusing on causal relationships in genome regulation, a new AI method could help scientists identify new immunotherapy techniques or regenerative therapies.