An ancient RNA-guided system could simplify delivery of gene editing therapies
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
Genetics
With generative AI, MIT chemists quickly calculate 3D genomic structures
A new approach, which takes minutes rather than days, predicts how a specific DNA sequence will arrange itself in the cell nucleus.
A causal theory for studying the cause-and-effect relationships of genes
By sidestepping the need for costly interventions, a new method could potentially reveal gene regulatory programs, paving the way for targeted treatments.
A more effective experimental design for engineering a cell into a new state
By focusing on causal relationships in genome regulation, a new AI method could help scientists identify new immunotherapy techniques or regenerative therapies.