Rationale engineering generates a compact new tool for gene therapy
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
FragFold, developed by MIT Biology researchers, is a computational method with potential for impact on biological research and therapeutic applications.