Rationale engineering generates a compact new tool for gene therapy
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.
A quarter century after its founding, the McGovern Institute reflects on its discoveries in the areas of neuroscience, neurotechnology, artificial intelligence, brain-body connections, and therapeutics.
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.