Proteins
Proteins

Proteins

Algorithms Artificial Intelligence Biology Computer Science and Artificial Intelligence Laboratory (CSAIL) Computer science and technology DNA Drug development Electrical Engineering & Computer Science (eecs) Jameel Clinic machine learning Medicine MIT Schwarzman College of Computing Pharmaceuticals Proteins Research School of Engineering

Generative AI imagines new protein structures

MIT researchers develop “FrameDiff,” a computational tool that uses generative AI to craft new protein structures, with the aim of accelerating drug development and improving gene therapy.

Artificial Intelligence Biological engineering Broad Institute Computer Science and Artificial Intelligence Laboratory (CSAIL) Computer science and technology Drug discovery Electrical engineering and computer science (EECS) machine learning Mathematics MIT Schwarzman College of Computing National Institutes of Health (NIH) National Science Foundation (NSF) Proteins Ragon Institute Research School of Engineering School of Science

New model offers a way to speed up drug discovery

By applying a language model to protein-drug interactions, researchers can quickly screen large libraries of potential drug compounds.

Algorithms Artificial Intelligence Bioinspiration Civil and environmental engineering Computer science and technology Department of Energy (DoE) machine learning Materials science and engineering MIT Schwarzman College of Computing MIT-IBM Watson AI Lab National Institutes of Health (NIH) Proteins Research School of Engineering

AI system can generate novel proteins that meet structural design targets

These tunable proteins could be used to create new materials with specific mechanical properties, like toughness or flexibility.

Artificial Intelligence Bacteria Bioengineering and biotechnology Biological engineering Brain and cognitive sciences Broad Institute Cells Drug delivery McGovern Institute Nanoscience and nanotechnology Proteins Research School of Engineering School of Science

Bacterial injection system delivers proteins in mice and human cells

With further development, the programmable system could be used in a range of applications including gene and cancer therapies.